Acitretin is the active ingredient in the medication.It belongs to a class of drugs called retinoids, which are related to vitamin A.
Severe, recalcitrant psoriasis (plaque psoriasis) that has not responded to other treatments.
Severe palmoplantar pustulosis (a skin condition affecting the palms of the hands and soles of the feet).
A Tret 25mg Cap (Acitretin) works by reducing the rapid growth of skin cells, which is a characteristic of psoriasis. It also reduces inflammation and helps to normalize the skin's appearance.
Store acitretin capsules at room temperature, between 15°C and 30°C (59°F and 86°F). Keep them away from direct sunlight and moisture.
The dosage of acitretin is determined by your doctor and depends on your condition and response to treatment.
It is usually taken once a day with a meal.
It is important to take acitretin exactly as prescribed by your doctor. Do not take more or less of it than prescribed.
Increased levels of cholesterol and triglycerides (fats) in the blood
Birth defects (in women who are pregnant or may become pregnant)
Dry skin, lips, and mucous membranes
Headache
Muscle or joint pain
Liver problems
Depression, anxiety, and mood changes
Alcohol can increase the risk of liver problems, so it is best to avoid alcohol while taking acitretin.
Acitretin can cause dizziness or drowsiness, so it is best to avoid driving or operating machinery until you know how this medication affects you.
Acitretin is very dangerous to a developing fetus and should not be used by pregnant or breastfeeding women. Effective contraception is essential for women of childbearing potential.
Acitretin is not approved for use in children.
Acitretin can affect kidney function, so it is important to monitor your kidney function regularly while taking this medication.
Acitretin can affect liver function, so it is important to monitor your liver function regularly while taking this medication.
The prescribing information for acitretin.
The National Psoriasis Foundation website.
The American Academy of Dermatology website.
Your doctor or pharmacist.
