A sulfonylurea drug that stimulates the pancreas to release more insulin.
A thiazolidinedione (tzd) that improves insulin sensitivity in the body's tissues.
A biguanide that reduces glucose production in the liver and improves insulin sensitivity.
Type 2 diabetes mellitus when diet and exercise alone are not sufficient to control blood sugar levels.
Used in patients who require a combination therapy to effectively manage their blood sugar.
This triple combination medication works synergistically to manage blood sugar levels. Gliclazide stimulates insulin release, pioglitazone enhances insulin sensitivity in tissues, and metformin reduces hepatic glucose production and improves insulin sensitivity. This combined effect leads to better blood glucose control.
Store in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children.
Dosage should be determined by a healthcare professional based on individual patient needs and response.
Typically, the medication is taken orally with meals to minimize gastrointestinal side effects.
The dosage may be gradually increased as directed by the doctor to achieve optimal blood sugar control.
Hypoglycemia (low blood sugar): Symptoms can include sweating, shakiness, dizziness, and confusion.
Liver problems (rare but serious, requires monitoring).
Gastrointestinal issues: Nausea, vomiting, diarrhea, and abdominal pain.
Weight gain (especially with pioglitazone).
Fluid retention (with pioglitazone).
Allergic reactions (rash, itching, swelling).
Alcohol can increase the risk of hypoglycemia. Avoid excessive alcohol consumption.
Hypoglycemia can impair cognitive function and reaction time. Avoid driving or operating machinery if experiencing symptoms of hypoglycemia.
Not generally recommended during pregnancy and breastfeeding. Consult with a healthcare professional immediately.
Not usually prescribed for children. Consult a pediatrician.
Dosage adjustments are necessary for patients with kidney impairment. Regular kidney function monitoring is crucial.
Regular liver function tests are necessary, especially with pioglitazone. The drug may be contraindicated in patients with severe liver disease.
Consult your physician or pharmacist for detailed information and drug interactions.
Refer to the official drug monograph for complete details.
