Glibenclamide

A sulfonylurea drug that helps your pancreas release more insulin.

Metformin

A biguanide drug that helps your body use insulin more effectively.

Rosiglitazone

A thiazolidinedione drug that helps your body become more sensitive to insulin.

Type 2 diabetes mellitus when diet and exercise alone are not enough to control blood sugar levels.

This combination medication works by improving your body's response to insulin. Glibenclamide stimulates the release of insulin from your pancreas, while metformin reduces the production of glucose by your liver and increases your body's sensitivity to insulin. Rosiglitazone increases insulin sensitivity in your body's tissues, allowing them to use glucose more efficiently.

Store the medication in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets.

The dosage of this medication will vary depending on your individual needs and response to treatment. Your doctor will determine the appropriate dosage for you.

This medication is typically taken orally with meals. It's important to take the medication exactly as prescribed by your doctor and not skip doses.

If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. Don't take a double dose to make up for a missed dose.

Do not stop taking this medication without consulting your doctor, even if you feel well. Stopping abruptly can increase your blood sugar levels.

Serious side effects can occur, including lactic acidosis (a build-up of lactic acid in the blood), heart failure, and liver problems.

Common side effects include nausea, vomiting, diarrhea, stomach pain, headache, dizziness, and weight gain.

Alcohol Consumption

Alcohol can interfere with the effectiveness of this medication and increase the risk of low blood sugar. Limit or avoid alcohol consumption while taking this medication.



While Driving or Operating Machinery

This medication may cause dizziness or drowsiness. Avoid driving or operating machinery until you know how this medication affects you.



Pregnant & Breastfeeding Women

This medication is not recommended for pregnant or breastfeeding women. Discuss the risks and benefits with your doctor if you are pregnant or breastfeeding.



Children

This medication is not approved for use in children.



Kidney

This medication is not recommended for people with severe kidney disease.



Liver

This medication is not recommended for people with severe liver disease.

https://www.medicines.org.uk/

https://www.nhs.uk/

https://www.fda.gov/