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Prepulsid 5mg Tablet
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Cisapride (5mg)
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About Prepulsid 5mg Tablet
Prepulsid 5mg Tablet (Cisapride) is a medication that was once used to treat GERD and gastroparesis. However, due to a significant risk of serious heart rhythm problems, its use is now extremely limited and only under strict medical supervision. If prescribed, it is crucial to follow your doctor's instructions precisely and report any unusual symptoms, particularly heart palpitations or dizziness, immediately. This medication should not be taken without explicit instruction from a physician.
Ingredients of Prepulsid 5mg Tablet

    Cisapride

    Cisapride (active ingredient)Inactive ingredients (vary by formulation – check product label)

Direction for Use of Prepulsid 5mg Tablet

Treatment of gastroesophageal reflux disease (GERD) – Note: Cisapride is largely withdrawn from the market in many countries due to serious cardiac risks. Its use is generally restricted to situations where other treatments have failed and under very close medical supervision.

    Relief of symptoms associated with gastroparesis (delayed stomach emptying)

How Prepulsid 5mg Tablet Works

Prepulsid 5mg Tablet (Cisapride) increases the motility of the gastrointestinal tract by stimulating serotonin receptors (5-HT4). This accelerates gastric emptying and improves esophageal sphincter function.

Storage and Handling of Prepulsid 5mg Tablet

Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children. Discard according to your pharmacist’s instructions.

Dosage of Prepulsid 5mg Tablet

    Dosage must be determined by a physician and will vary depending on the patient's condition and response to treatment.

    Always follow prescribed dosage and frequency exactly.

Side effects of Prepulsid 5mg Tablet

    Prolonged QT interval (ECG abnormality)

    Diarrhea

    Headache

    Nausea

    Abdominal pain

Safety Consideration or Warnings
    Alcohol Consumption

    Avoid alcohol consumption as it can increase the risk of side effects, especially cardiac issues.

    While Driving or Operating Machinery

    May cause drowsiness or dizziness. Avoid operating machinery or driving until you know how cisapride affects you.

    Pregnant & Breastfeeding Women

    Use only if clearly needed and under close medical supervision. The potential benefits must outweigh the potential risks to the fetus or infant.

    Children

    Use in children is generally not recommended due to safety concerns.

    Kidney

    Caution should be exercised in patients with impaired kidney function. Dosage adjustment may be necessary.

    Liver

    Caution should be exercised in patients with impaired liver function. Dosage adjustment may be necessary.

References

    Consult your physician or pharmacist for detailed information and references.

    Reputable medical databases and journals (e.g., PubMed)

Last Updated On 29 Aug. 2025 | 09:45 PM (IST)
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