Pefloxacin

Is a type of antibiotic known as a fluoroquinolone.

Pefloxacin is used to treat a variety of bacterial infections, including:

Infections of the respiratory tract (e.g., pneumonia, bronchitis)

Infections of the urinary tract (e.g., cystitis, pyelonephritis)

Skin and soft tissue infections

Infections of the bones and joints

Gonorrhea

Pefan 400mg Tablet (Pefloxacin) works by inhibiting the enzyme DNA gyrase, which is essential for bacterial DNA replication. By blocking this enzyme, pefloxacin prevents bacterial growth and ultimately kills the bacteria.

Store pefloxacin at room temperature, away from moisture and direct sunlight. Keep it out of reach of children and pets.

The dosage of pefloxacin will vary depending on the type of infection being treated and the patient's individual needs. It is typically taken by mouth, either with or without food.

Always follow your doctor's instructions carefully and take the exact dosage prescribed. Do not take more or less than directed.

Do not stop taking pefloxacin prematurely, even if you start to feel better. Completing the full course of treatment is important to ensure the infection is fully cleared and prevent antibiotic resistance.

Like all medications, pefloxacin can cause side effects, although not everyone experiences them. Some common side effects include:

In rare cases, pefloxacin can cause more serious side effects, such as:

Nausea

Vomiting

Diarrhea

Headache

Dizziness

Stomach pain

Rash

Itching

Seizures

Tendinitis (inflammation of the tendons)

Tendon rupture

Liver damage

Kidney damage

Allergic reactions (e.g., rash, itching, swelling, difficulty breathing)

Alcohol Consumption

Drinking alcohol while taking pefloxacin may increase the risk of side effects, especially dizziness. It's best to avoid alcohol while taking this medication.



While Driving or Operating Machinery

Pefloxacin can cause dizziness, drowsiness, and other side effects that may impair your ability to drive or operate machinery. It's important to avoid these activities until you know how the medication affects you.



Pregnant & Breastfeeding Women

Pefloxacin should only be used during pregnancy if the potential benefits outweigh the risks to the developing baby. It is not recommended for use during breastfeeding.



Children

The use of pefloxacin in children is generally not recommended, as there is limited safety and effectiveness data available.



Kidney

Pefloxacin can be harmful to the kidneys, especially in people with pre-existing kidney problems. Your doctor may need to adjust your dosage or monitor your kidney function if you have kidney disease.



Liver

Pefloxacin can also cause liver damage. Your doctor may monitor your liver function if you have a history of liver problems.

1. https://www.drugs.com/pefloxacin.html

2. https://www.rxlist.com/pefloxacin-drug.htm

3. https://pubchem.ncbi.nlm.nih.gov/compound/Pefloxacin