Vinorelbine

Vinorelbine is the active ingredient in this medication.It is available in different formulations, including intravenous injection, oral capsules, and liposomal injection, each with its specific inactive ingredients.

Vinorelbine is primarily used to treat various types of cancer, including:

Non-small cell lung cancer

Breast cancer

Ovarian cancer

Hodgkin's lymphoma

Other cancers as determined by your doctor.

Navelbine 10mg/10ml Inj (Vinorelbine) is a chemotherapy drug classified as a vinca alkaloid. It works by interfering with the cell division process, specifically by inhibiting the formation of microtubules, essential structures within cells that aid in cell division.

Store vinorelbine as instructed by your doctor or pharmacist, usually at room temperature, protected from light and moisture. Keep it out of reach of children and pets. Do not use the medication after its expiry date.

The dosage of vinorelbine will be determined by your doctor based on your condition, age, and other factors.

It is typically administered intravenously over a specific time period.

For oral formulations, follow the instructions provided by your doctor and pharmacist carefully.

Do not adjust the dosage or frequency without consulting your doctor.

Common side effects include:

Severe side effects are less common but can include:

Nausea and vomiting

Hair loss

Fatigue

Low blood cell counts (neutropenia, anemia, thrombocytopenia)

Mouth sores

Constipation

Peripheral neuropathy (numbness or tingling in the hands and feet)

Severe allergic reactions

Heart problems

Liver damage

Pulmonary toxicity

Seizures

Neurological complications

Alcohol Consumption

Avoid alcohol consumption while on vinorelbine, as it may increase the risk of side effects, especially liver damage.



While Driving or Operating Machinery

Vinorelbine can cause fatigue and dizziness, so avoid driving or operating machinery if you experience these side effects.



Pregnant & Breastfeeding Women

Vinorelbine is a teratogenic drug, meaning it can cause birth defects. It should not be used during pregnancy or breastfeeding. Consult your doctor immediately if you become pregnant or are planning to become pregnant while on this medication.



Children

Vinorelbine is not typically prescribed for children.



Kidney

Your doctor may need to adjust your dosage if you have kidney problems.



Liver

Vinorelbine can affect liver function. If you have liver problems, your doctor will monitor you closely.

National Cancer Institute (NCI): https://www.cancer.gov/publications/dictionaries/cancer-terms/def/vinorelbine

Drugs.com: https://www.drugs.com/mtm/vinorelbine.html

Mayo Clinic: https://www.mayoclinic.org/diseases-conditions/cancer/expert-answers/vinorelbine/faq-20058018