Is the active ingredient in mitomycin-containing medications. specific formulations may contain additional inactive ingredients such as preservatives, stabilizers, or diluents. always check the medication label for a complete list of ingredients.
Treatment of various cancers, including bladder cancer (intravesical instillation), stomach cancer, and pancreatic cancer (in combination with other chemotherapeutic agents).
Treatment of other solid tumors may also be possible based on the advice of an oncologist
Mitomycin C 40mg Inj (Mitomycin) is an alkylating agent and an antitumor antibiotic. It interferes with DNA replication and repair, leading to cell death, primarily in rapidly dividing cancer cells. The specific mechanism involves the formation of DNA cross-links, preventing cell division.
Store mitomycin as directed by the pharmacist or healthcare provider. Typically, this involves storing it at a controlled room temperature, away from direct sunlight and moisture. Never freeze mitomycin. Dispose of unused medication according to instructions provided by your healthcare provider or local regulations. Always handle with caution, avoiding direct skin contact.
Dosage and administration methods vary widely depending on the specific cancer type, treatment regimen, and the patient's overall health. Dosages are determined and administered by trained medical professionals such as oncologists and nurses.
Common routes of administration include intravenous infusion, intra-arterial infusion, and intravesical instillation (directly into the bladder).
Nausea and vomiting
Diarrhea
Alopecia (hair loss)
Kidney damage
Pulmonary toxicity (lung damage)
Infections
Bleeding
Mucositis (inflammation of mucous membranes)
Fatigue
Alcohol consumption may exacerbate some side effects, particularly nausea and vomiting. Discuss alcohol consumption with your doctor.
Mitomycin can cause fatigue and other side effects that may impair your ability to drive or operate machinery. Avoid these activities if affected.
Mitomycin is teratogenic (can cause birth defects) and should not be used during pregnancy or by breastfeeding women unless the potential benefits significantly outweigh the risks. Discuss this thoroughly with your oncologist.
Dosage and safety considerations for children may differ significantly from adults. Pediatric oncologists will determine appropriate dosing and monitor the child closely.
Kidney function should be closely monitored as mitomycin can cause nephrotoxicity (kidney damage).
Liver function should also be closely monitored during mitomycin treatment.
Your Oncologist
Prescribing Information for mitomycin-containing medications
Peer-reviewed medical journals (specific articles can be provided upon request from your physician)
