Mitomycin

Is the active ingredient in mitomycin-containing medications. specific formulations may contain additional excipients (inactive ingredients) to aid in drug delivery and stability. always check the medication label for a complete list of ingredients.

Treatment of various types of cancer, including bladder cancer (intravesical instillation), stomach cancer, pancreatic cancer, and colorectal cancer (often in combination with other chemotherapy agents).

Use is typically determined by a physician based on the type and stage of cancer.

Mitomycin 2mg Inj (Mitomycin) is an alkylating agent and an antitumor antibiotic. It works by damaging the DNA of cancer cells, preventing their replication and ultimately leading to cell death. Its mechanism involves forming cross-links between DNA strands, inhibiting DNA replication and transcription.

Mitomycin formulations should be stored according to the specific instructions on the product label. Generally, this involves refrigeration and protection from light. Never use a medication past its expiration date.

Dosage and administration route vary significantly depending on the specific cancer being treated, the patient's overall health, and the physician's treatment plan.

Mitomycin can be administered intravenously (IV), intra-arterially (directly into an artery), or intravesically (directly into the bladder).

Dosage is typically calculated based on body surface area (BSA) or body weight and is determined and carefully monitored by an oncologist.

Nausea and vomiting

Diarrhea

Hair loss (alopecia)

Mouth sores (mucositis)

Kidney damage

Lung damage (pulmonary toxicity)

Infections due to weakened immune system

Severe allergic reactions (rare)

Alcohol Consumption

Alcohol consumption should be discussed with your doctor. It may exacerbate some side effects, particularly nausea and vomiting.



While Driving or operating Machinery

Mitomycin can cause fatigue and other side effects that may impair your ability to drive or operate machinery. Avoid these activities if affected.



Pregnant & Breastfeeding Women

Mitomycin is known to be harmful to a developing fetus. It is contraindicated during pregnancy. Women should discuss with their doctor the risks associated with pregnancy and breastfeeding while undergoing mitomycin treatment. Breastfeeding is usually not recommended.



Children

The use of mitomycin in children is usually limited to specific circumstances and is carefully considered by oncologists due to the increased risk of side effects.



Kidney

Pre-existing kidney problems may be worsened by mitomycin. Kidney function is closely monitored during treatment.



Liver

Liver function should be evaluated before and during mitomycin treatment, as liver toxicity can occur.

Consult your physician or oncologist for detailed information and references related to your specific treatment plan. The prescribing information for the specific mitomycin formulation you are using will contain further details.