Dacarbazine

Dacarbazine is the active ingredient in the medication.It is an antineoplastic drug, specifically a methylating agent.

Dacarbazine is used to treat certain types of cancer, including:

Hodgkin's lymphoma

Non-Hodgkin's lymphoma

Malignant melanoma

Soft tissue sarcoma

Brain tumors

Melarylz 200mg Injection (Dacarbazine) works by interfering with the growth and division of cancer cells. It does this by alkylating DNA, a process that damages the DNA and prevents the cancer cells from replicating.

Dacarbazine should be stored at room temperature, away from direct sunlight and moisture.

The dosage and frequency of dacarbazine administration will depend on the type and stage of cancer being treated, the patient's overall health, and other factors.

It is typically given intravenously (into a vein) or as a single dose or in multiple doses over a period of time.

Dacarbazine is usually given in a hospital or clinic setting.

It is important to follow your doctor's instructions carefully and do not change the dosage or frequency of your medication without their approval.

Like all medications, dacarbazine can cause side effects.

Some common side effects include:

Serious side effects can occur, including:

Nausea and vomiting

Diarrhea

Loss of appetite

Hair loss

Fatigue

Skin rash

Low blood cell counts (anemia, neutropenia, thrombocytopenia)

Liver problems

Kidney problems

Infusion reactions

Severe infections

Bleeding

Heart problems

Lung problems

Second cancers

Alcohol Consumption

It is generally recommended to avoid alcohol consumption while taking dacarbazine, as it can increase the risk of liver damage.



While Driving or operating Machinery

Dacarbazine can cause fatigue and other side effects that may impair your ability to drive or operate machinery. It is best to avoid these activities until you know how dacarbazine affects you.



Pregnant & Breastfeeding Women

Dacarbazine is known to be harmful to the fetus and is not recommended for use during pregnancy. It is also not recommended for use during breastfeeding, as it may pass into breast milk.



Children

Dacarbazine is not typically used in children, unless it is considered absolutely necessary for the treatment of their cancer.



Kidney

Patients with kidney problems may need to have their dacarbazine dosage adjusted.



Liver

Patients with liver problems may need to have their dacarbazine dosage adjusted.

National Cancer Institute (NCI): https://www.cancer.gov/

Drugs.com: https://www.drugs.com/

Mayo Clinic: https://www.mayoclinic.org/

Your doctor or pharmacist can provide you with more information about dacarbazine.