Acetate is the active ingredient in medications containing this drug. formulations may vary, including depot injections, implants, and nasal sprays, with varying excipients (inactive ingredients) depending on the specific product.
Treatment of advanced prostate cancer
Treatment of uterine fibroids (leiomyomas)
Treatment of endometriosis
Treatment of precocious puberty
Treatment of central precocious puberty
In conjunction with other treatments for certain types of breast cancer
Materna Depot 3.75mg Inj (Leuprolide) is a gonadotropin-releasing hormone (GnRH) agonist. It initially stimulates the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), but with prolonged use, it suppresses their production. This leads to a decrease in the production of sex hormones (testosterone in men and estrogen in women), which is the basis for its therapeutic effects in various conditions.
Store according to the specific instructions on the product label. Generally, this involves refrigeration or room temperature storage, protection from light, and keeping out of reach of children.
Dosage varies significantly depending on the indication, patient factors, and formulation (injection, implant, nasal spray).
It's crucial to follow the prescribed dosage and administration schedule provided by your doctor. Never adjust the dosage or frequency on your own.
Injections are typically administered by a healthcare professional.
Implants are surgically placed.
Nasal sprays require careful adherence to instructions for proper administration.
Hot flashes
Decreased libido
Erectile dysfunction (men)
Vaginal dryness (women)
Bone loss (osteoporosis)
Mood changes (depression, anxiety)
Weight changes
The interaction between leuprolide and alcohol is not well-established. However, it's generally advised to moderate alcohol consumption, especially if experiencing side effects such as mood changes.
Leuprolide may cause drowsiness or dizziness in some individuals, particularly at the beginning of treatment. If affected, avoid driving or operating machinery until these side effects subside.
Leuprolide is generally not recommended during pregnancy or breastfeeding due to potential fetal harm. Discuss this with your doctor before starting treatment.
Used only in specific conditions like precocious puberty, under strict medical supervision and only when the benefits outweigh the risks.
Patients with kidney impairment may require dosage adjustments. Your doctor will determine the appropriate dosage based on your kidney function.
Information on liver-specific adjustments is generally not readily available. Consult your physician about specific liver concerns.
Your doctor or healthcare provider
The medication's package insert
Reputable medical websites (e.g., Mayo Clinic, MedlinePlus)
