Magnesium valproate is the magnesium salt of valproic acid.It contains the active ingredient valproate, which is an anticonvulsant and mood stabilizer.
Treatment of epilepsy and related seizure disorders (tonicclonic, absence, myoclonic, and mixed seizures).
Treatment of bipolar disorder (manic episodes).
Treatment of migraine headaches (prophylactically).
The exact mechanism of action isn't fully understood, but valproate is thought to increase levels of the neurotransmitters GABA (gamma-aminobutyric acid) and to affect sodium and calcium channels in neurons, thus reducing neuronal excitability and preventing seizures.
Store at room temperature (20-25°C) in a dry place away from light and moisture. Keep out of reach of children. Dispose of unused medication properly according to local guidelines.
Dosage is determined by the doctor based on the patient's age, weight, condition, and response to treatment.
It is usually administered orally, either as a tablet or liquid suspension.
Always follow the prescription instructions precisely.
Do not abruptly stop taking magnesium valproate without consulting your doctor.
Nausea and vomiting
Weight gain
Hair loss
Tremor
Drowsiness
Sedation
Liver problems (rare but serious)
Pancreatitis (rare but serious)
Thrombocytopenia (low platelet count)
Alcohol should be avoided or consumed very sparingly while taking magnesium valproate, as it can increase the risk of side effects.
Avoid driving or operating machinery until you know how magnesium valproate affects you. It can cause drowsiness and impair cognitive function.
Magnesium valproate is generally avoided during pregnancy due to the risk of birth defects. It can also pass into breast milk, potentially affecting the infant. Discuss risks and alternatives with your doctor.
Dosage and monitoring are crucial for children. A doctor will carefully adjust the dosage based on the child's age, weight, and condition.
Kidney impairment may require dosage adjustment. Your doctor will monitor kidney function.
Liver function tests are often performed regularly while taking magnesium valproate, especially during the initial phase of treatment, due to the risk of liver damage.
This information is for general knowledge and does not constitute medical advice. Always consult your doctor or pharmacist for specific guidance on magnesium valproate.
