Citrate a selective estrogen receptor modulator (serm) that stimulates the release of gonadotropins (fsh and lh) from the pituitary gland.
An antioxidant that plays a vital role in energy production within cells. its role in combination with clomiphene is under ongoing research.
Treatment of ovulatory dysfunction in women who desire pregnancy (Clomiphene's primary indication; CoQ10's role is supportive and not definitively established for this purpose).
Infertility in women with anovulation (lack of ovulation).
Clomiphene acts by blocking estrogen receptors in the hypothalamus and pituitary gland. This leads to a decrease in negative feedback, resulting in increased release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH). Increased FSH and LH stimulate follicle development and ovulation. The precise mechanism of action for CoQ10 in this combination is not fully understood, but it's hypothesized to improve ovarian function by supporting mitochondrial function and reducing oxidative stress. More research is needed to definitively establish its synergistic effect with clomiphene.
Store in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children. Follow the specific storage instructions provided on the medication label.
Dosage of Clomiphene Citrate and CoQ10 should be determined by a healthcare professional, individualised to the patient's needs and response.
Clomiphene is typically administered orally, starting with a low dose and increasing it gradually if necessary. The exact dosage and duration vary.
CoQ10 is also generally administered orally. The dosage varies depending on the specific formulation.
Multiple pregnancies (twins, triplets, etc.)
Ovarian hyperstimulation syndrome (OHSS)
Visual disturbances (blurred vision, light sensitivity)
Hot flashes
Headaches
Nausea
Breast tenderness
Mood changes
Weight changes
Moderate alcohol consumption may be acceptable, but excessive alcohol use should be avoided during treatment.
Patients should be cautious about operating machinery or driving if experiencing side effects such as visual disturbances.
Not indicated for use during pregnancy or breastfeeding. Consult your physician.
Not indicated for use in children.
Caution is advised in patients with kidney disease. Dosage adjustments may be necessary.
Caution is advised in patients with liver disease. Dosage adjustments may be necessary.
Consult your physician or pharmacist for specific references and updated information.
Reputable medical journals and databases (e.g., PubMed).
