Estradiol

Is the primary active ingredient. formulations may include various inactive ingredients depending on the specific product (e.g., fillers, binders, preservatives). always check the product label for a complete list of ingredients.

Hormone replacement therapy (HRT) for menopausal symptoms like hot flashes, vaginal dryness, and night sweats.

Treatment of hypogonadism (low levels of sex hormones) in women.

Prevention of osteoporosis in postmenopausal women.

Treatment of certain types of breast cancer (in combination with other therapies).

Endogain Gel 80gm (Estradiol) binds to estrogen receptors in various tissues throughout the body. This binding initiates a cascade of cellular events that lead to the characteristic effects of estrogen, including the alleviation of menopausal symptoms and the promotion of bone health.

Store at room temperature, away from direct sunlight and moisture. Keep out of reach of children. Discard expired medication properly.

Dosage varies significantly depending on the individual's condition, age, and response to treatment. Always follow the prescription provided by your doctor.

Estradiol is available in various forms, including pills, patches, gels, creams, and implants. The route of administration will depend on the prescription.

Do not alter your dosage or stop taking the medication without consulting your doctor.

Breast tenderness or enlargement

Fluid retention

Headache

Nausea

Vaginal bleeding or spotting

Mood changes

Increased risk of blood clots (thromboembolism)

Alcohol Consumption

The interaction between estradiol and alcohol is not well-established. Moderate alcohol consumption may be acceptable but should be discussed with your doctor.



While Driving or operating Machinery

Estradiol may cause drowsiness or dizziness in some individuals. Avoid driving or operating machinery if affected.



Pregnant & Breastfeeding Women

Estradiol is generally not recommended during pregnancy or breastfeeding unless specifically prescribed by a doctor. It can pass into breast milk.



Children

Estradiol is not typically used in children.



Kidney

Renal impairment may affect estradiol metabolism. Dosage adjustments may be necessary. Consult your doctor.



Liver

Hepatic impairment can also alter estradiol metabolism. Dosage adjustments may be necessary. Consult your doctor.

Your prescribing physician

The product’s package insert

Reputable medical websites (e.g., Mayo Clinic, MedlinePlus)