A sulfonamide antibiotic that prevents bacteria from producing folic acid, a vital nutrient for their growth and survival.
A dihydrofolate reductase inhibitor that also interferes with folic acid production in bacteria, enhancing the antibacterial effect of sulfamethoxazole.
Treatment of urinary tract infections (UTIs)
Treatment of acute exacerbations of chronic bronchitis
Treatment of uncomplicated skin and soft tissue infections
Treatment of traveler's diarrhea (certain types)
Prophylaxis of Pneumocystis jirovecii pneumonia (PCP) in immunocompromised individuals (often requires a higher dose)
Ciplin Tab (Sulfamethoxazole + Trimethoprim) act synergistically. Sulfamethoxazole inhibits dihydropteroate synthetase, an enzyme crucial for folic acid synthesis. Trimethoprim inhibits dihydrofolate reductase, another enzyme in the same pathway. By inhibiting sequential steps in folic acid production, bacterial growth is significantly suppressed.
Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children.
Dosage varies depending on the infection being treated and the patient's age and health status. Always follow your doctor's prescription.
The medication is typically taken orally, with or without food.
Complete the entire course of antibiotics, even if symptoms improve, to prevent recurrence and antibiotic resistance.
Nausea
Vomiting
Diarrhea
Rash
Itching
Headache
Dizziness
Photosensitivity
Blood disorders (rare but serious)
Allergic reactions (in rare cases, severe)
Alcohol consumption may increase the risk of side effects. Consult your doctor.
May cause drowsiness or dizziness. Avoid driving or operating machinery until you know how this medication affects you.
Use during pregnancy and breastfeeding should be carefully considered. Consult your doctor before using this medication.
Dosage adjustments are necessary for children. Consult your doctor.
Renal impairment can affect the drug's elimination; dosage adjustment is usually required. Close monitoring is recommended.
Liver impairment may affect metabolism and necessitate dosage adjustments. Close monitoring is advised.
Your doctor or pharmacist
The package leaflet provided with your medication
Reputable medical websites such as the FDA or NHS
