Is the active ingredient in medications formulated for treating alcohol use disorder and opioid use disorder.
Treatment of alcohol use disorder (AUD) in adults who are motivated to abstain from alcohol.
Treatment of opioid use disorder (OUD) in adults who are also receiving opioid agonist therapy (e.g., methadone or buprenorphine) or who have recently stopped using opioids.
Naltrexone may also be used offlabel for other purposes, such as reducing cravings for other substances or managing certain medical conditions, but these uses require further research and should be discussed with a healthcare professional.
Addtrex Tab (Naltrexone) works by blocking the effects of opioids in the brain. It binds to opioid receptors, preventing opioids (including heroin, morphine, and other prescription pain relievers) from binding and activating them. This blockade helps reduce cravings and withdrawal symptoms, making it easier for individuals to maintain abstinence from alcohol and opioids.
Store naltrexone at room temperature, away from light and moisture. Keep it out of reach of children and pets. Do not flush unused medication down the toilet or pour it into a drain. Dispose of it properly or return it to a pharmacy for safe disposal.
The dosage of naltrexone varies depending on the condition being treated and the individual's needs. Your doctor will determine the appropriate dose for you.
Naltrexone is usually taken by mouth once daily. It can be taken with or without food.
Naltrexone is available in different formulations, including tablets, extended-release tablets, and injections. The specific formulation and dosage will be prescribed by your doctor.
Common side effects of naltrexone include headache, nausea, vomiting, diarrhea, abdominal pain, fatigue, and dizziness.
Naltrexone is specifically indicated for alcohol use disorder, but it's crucial to note that consuming alcohol while taking naltrexone can be dangerous. It may lead to serious side effects, including liver damage. It's essential to follow your doctor's instructions regarding alcohol consumption while on naltrexone.
Naltrexone can cause dizziness, drowsiness, and other side effects that might impair your ability to drive or operate machinery. Avoid these activities if you experience such effects until you feel fully alert.
Naltrexone is not recommended during pregnancy unless the potential benefits outweigh the risks. It's crucial to discuss this with your doctor. Naltrexone can pass into breast milk, and its effects on a nursing infant are unknown. Consult your doctor about whether it's safe to breastfeed while taking naltrexone.
Naltrexone is not approved for use in children. It should not be given to children unless specifically prescribed by a doctor.
Naltrexone is primarily processed by the liver and is not significantly affected by kidney function. However, if you have severe kidney disease, your doctor might adjust your dosage.
Naltrexone is primarily metabolized by the liver. If you have liver disease, your doctor might need to adjust your dosage or monitor your liver function closely. In some cases, naltrexone might not be suitable for individuals with severe liver problems.
National Institute on Drug Abuse (NIDA): https://www.drugabuse.gov/
Food and Drug Administration (FDA): https://www.fda.gov/
Centers for Disease Control and Prevention (CDC): https://www.cdc.gov/
